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Identification of VEGF Signaling Inhibition-Induced Glomerular Injury in Rats through Site-Specific Urinary Biomarkers

Cancer therapies targeting the vascular endothelial growth factor (VEGF) signaling pathway can lead to renal damage by disrupting the glomerular ultrafiltration apparatus. The objective of the current study was to identify sensitive biomarkers for VEGF inhibition-induced glomerular changes in rats....

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Detalles Bibliográficos
Autores principales: Yang, Yi, Kowalkowski, Kenneth, Ciurlionis, Rita, Buck, Wayne R., Glaser, Keith B., Albert, Daniel H., Blomme, Eric A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657489/
https://www.ncbi.nlm.nih.gov/pubmed/34884436
http://dx.doi.org/10.3390/ijms222312629