Topoisomerase IIIβ Deficiency Induces Neuro-Behavioral Changes and Brain Connectivity Alterations in Mice

Topoisomerase IIIβ (Top3β), the only dual-activity topoisomerase in mammals that can change topology of both DNA and RNA, is known to be associated with neurodevelopment and mental dysfunction in humans. However, there is no report showing clear associations of Top3β with neuropsychiatric phenotypes...

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Detalles Bibliográficos
Autores principales: Rahman, Faiz Ur, Kim, You-Rim, Kim, Eun-Kyeung, Kim, Hae-rim, Cho, Sang-Mi, Lee, Chin-Soo, Kim, Su Jin, Araki, Kimi, Yamamura, Ken-ichi, Lee, Mi-Ni, Park, Seul Gi, Yoon, Won-Kee, Lee, Kihoon, Won, Young-Suk, Kim, Hyoung-Chin, Lee, Younghee, Lee, Ho-Young, Nam, Ki-Hoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657541/
https://www.ncbi.nlm.nih.gov/pubmed/34884616
http://dx.doi.org/10.3390/ijms222312806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657541/
https://www.ncbi.nlm.nih.gov/pubmed/34884616
http://dx.doi.org/10.3390/ijms222312806

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