BRCA Mutations in Prostate Cancer: Assessment, Implications and Treatment Considerations

Prostate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is implicated in cancer and DNA damage response (DDR) pathways are in place against this to maintain genomic stability. Impaired DDR pathways play a role in prostate carcinogenesis and germline or somatic mutations...

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Detalles Bibliográficos
Autores principales: Shah, Sidrah, Rachmat, Rachelle, Enyioma, Synthia, Ghose, Aruni, Revythis, Antonios, Boussios, Stergios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657599/
https://www.ncbi.nlm.nih.gov/pubmed/34884434
http://dx.doi.org/10.3390/ijms222312628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657599/
https://www.ncbi.nlm.nih.gov/pubmed/34884434
http://dx.doi.org/10.3390/ijms222312628

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