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BRCA Mutations in Prostate Cancer: Assessment, Implications and Treatment Considerations
Prostate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is implicated in cancer and DNA damage response (DDR) pathways are in place against this to maintain genomic stability. Impaired DDR pathways play a role in prostate carcinogenesis and germline or somatic mutations...
Autores principales: | Shah, Sidrah, Rachmat, Rachelle, Enyioma, Synthia, Ghose, Aruni, Revythis, Antonios, Boussios, Stergios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657599/ https://www.ncbi.nlm.nih.gov/pubmed/34884434 http://dx.doi.org/10.3390/ijms222312628 |
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