Enhancing Paraoxon Binding to Organophosphorus Hydrolase Active Site

Organophosphorus hydrolase (OPH) is a metalloenzyme that can hydrolyze organophosphorus agents resulting in products that are generally of reduced toxicity. The best OPH substrate found to date is diethyl p-nitrophenyl phosphate (paraoxon). Most structural and kinetic studies assume that the binding...

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Detalles Bibliográficos
Autores principales: El Khoury, Léa, Mobley, David L., Ye, Dongmei, Rempe, Susan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657610/
https://www.ncbi.nlm.nih.gov/pubmed/34884430
http://dx.doi.org/10.3390/ijms222312624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657610/
https://www.ncbi.nlm.nih.gov/pubmed/34884430
http://dx.doi.org/10.3390/ijms222312624

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