Aptamer-Aptamer Chimera for Targeted Delivery and ATP-Responsive Release of Doxorubicin into Cancer Cells

Aptamers offer a great opportunity to develop innovative drug delivery systems that can deliver cargos specifically into targeted cells. In this study, a chimera consisting of two aptamers was developed to deliver doxorubicin into cancer cells and release the drug in cytoplasm in response to adenosi...

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Detalles Bibliográficos
Autores principales: Esawi, Ezaldeen, Alshaer, Walhan, Mahmoud, Ismail Sami, Alqudah, Dana A., Azab, Bilal, Awidi, Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657665/
https://www.ncbi.nlm.nih.gov/pubmed/34884745
http://dx.doi.org/10.3390/ijms222312940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657665/
https://www.ncbi.nlm.nih.gov/pubmed/34884745
http://dx.doi.org/10.3390/ijms222312940

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