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R-Loop Tracker: Web Access-Based Tool for R-Loop Detection and Analysis in Genomic DNA Sequences

R-loops are common non-B nucleic acid structures formed by a three-stranded nucleic acid composed of an RNA–DNA hybrid and a displaced single-stranded DNA (ssDNA) loop. Because the aberrant R-loop formation leads to increased mutagenesis, hyper-recombination, rearrangements, and transcription-replic...

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Detalles Bibliográficos
Autores principales: Brázda, Václav, Havlík, Jan, Kolomazník, Jan, Trenz, Oldřich, Šťastný, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657672/
https://www.ncbi.nlm.nih.gov/pubmed/34884661
http://dx.doi.org/10.3390/ijms222312857