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Dominant Role of PI3K p110α over p110β in Insulin and β-Adrenergic Receptor Signalling

Attribution of specific roles to the two ubiquitously expressed PI 3-kinase (PI3K) isoforms p110α and p110β in biological functions they have been implicated, such as in insulin signalling, has been challenging. While p110α has been demonstrated to be the principal isoform activated downstream of th...

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Detalles Bibliográficos
Autores principales: Zhang, Biqin, Luk, Cheukyau, Valadares, Joyce, Aronis, Christos, Foukas, Lazaros C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657683/
https://www.ncbi.nlm.nih.gov/pubmed/34884613
http://dx.doi.org/10.3390/ijms222312813