Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers

Amiodarone is a cationic amphiphilic drug used as an antiarrhythmic agent. It induces phospholipidosis, i.e., the accumulation of phospholipids within organelles of the endosomal–lysosomal system. Extracellular vesicles (EVs) are membrane-enclosed structures released by any type of cell and retrieve...

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Detalles Bibliográficos
Autores principales: Sagini, Krizia, Buratta, Sandra, Delo, Federica, Pellegrino, Roberto Maria, Giovagnoli, Stefano, Urbanelli, Lorena, Emiliani, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657686/
https://www.ncbi.nlm.nih.gov/pubmed/34884727
http://dx.doi.org/10.3390/ijms222312922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657686/
https://www.ncbi.nlm.nih.gov/pubmed/34884727
http://dx.doi.org/10.3390/ijms222312922

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