Enmein Decreases Synaptic Glutamate Release and Protects against Kainic Acid-Induced Brain Injury in Rats

This study investigated the effects of enmein, an active constituent of Isodon japonicus Hara, on glutamate release in rat cerebrocortical nerve terminals (synaptosomes) and evaluated its neuroprotective potential in a rat model of kainic acid (KA)-induced glutamate excitotoxicity. Enmein inhibited...

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Detalles Bibliográficos
Autores principales: Lu, Cheng-Wei, Huang, Yu-Chen, Chiu, Kuan-Ming, Lee, Ming-Yi, Lin, Tzu-Yu, Wang, Su-Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657722/
https://www.ncbi.nlm.nih.gov/pubmed/34884781
http://dx.doi.org/10.3390/ijms222312966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657722/
https://www.ncbi.nlm.nih.gov/pubmed/34884781
http://dx.doi.org/10.3390/ijms222312966

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