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Enmein Decreases Synaptic Glutamate Release and Protects against Kainic Acid-Induced Brain Injury in Rats
This study investigated the effects of enmein, an active constituent of Isodon japonicus Hara, on glutamate release in rat cerebrocortical nerve terminals (synaptosomes) and evaluated its neuroprotective potential in a rat model of kainic acid (KA)-induced glutamate excitotoxicity. Enmein inhibited...
Autores principales: | Lu, Cheng-Wei, Huang, Yu-Chen, Chiu, Kuan-Ming, Lee, Ming-Yi, Lin, Tzu-Yu, Wang, Su-Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657722/ https://www.ncbi.nlm.nih.gov/pubmed/34884781 http://dx.doi.org/10.3390/ijms222312966 |
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