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Biotin Transport-Targeting Polysaccharide-Modified PAMAM G3 Dendrimer as System Delivering α-Mangostin into Cancer Cells and C. elegans Worms

The natural xanthone α-mangostin (αM) exhibits a wide range of pharmacological activities, including antineoplastic and anti-nematode properties, but low water solubility and poor selectivity of the drug prevent its potential clinical use. Therefore, the targeted third-generation poly(amidoamine) de...

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Detalles Bibliográficos
Autores principales: Markowicz, Joanna, Uram, Łukasz, Wołowiec, Stanisław, Rode, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657743/
https://www.ncbi.nlm.nih.gov/pubmed/34884739
http://dx.doi.org/10.3390/ijms222312925