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N-acetylcysteine Can Induce Massive Oxidative Stress, Resulting in Cell Death with Apoptotic Features in Human Leukemia Cells

N-acetylcysteine (NAC), often used as an antioxidant-scavenging reactive oxygen species (ROS) in vitro, was recently shown to increase the cytotoxicity of other compounds through ROS-dependent and ROS-independent mechanisms. In this study, NAC itself was found to induce extensive ROS production in h...

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Detalles Bibliográficos
Autores principales: Mlejnek, Petr, Dolezel, Petr, Kriegova, Eva, Pastvova, Nikola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657769/
https://www.ncbi.nlm.nih.gov/pubmed/34884437
http://dx.doi.org/10.3390/ijms222312635