Development of a PROTAC-Based Targeting Strategy Provides a Mechanistically Unique Mode of Anti-Cytomegalovirus Activity

Human cytomegalovirus (HCMV) is a major pathogenic herpesvirus that is prevalent worldwide and it is associated with a variety of clinical symptoms. Current antiviral therapy options do not fully satisfy the medical needs; thus, improved drug classes and drug-targeting strategies are required. In pa...

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Detalles Bibliográficos
Autores principales: Hahn, Friedrich, Hamilton, Stuart T., Wangen, Christina, Wild, Markus, Kicuntod, Jintawee, Brückner, Nadine, Follett, Jasmine E. L., Herrmann, Lars, Kheimar, Ahmed, Kaufer, Benedikt B., Rawlinson, William D., Tsogoeva, Svetlana B., Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657773/
https://www.ncbi.nlm.nih.gov/pubmed/34884662
http://dx.doi.org/10.3390/ijms222312858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657773/
https://www.ncbi.nlm.nih.gov/pubmed/34884662
http://dx.doi.org/10.3390/ijms222312858

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