SB203580—A Potent p38 MAPK Inhibitor Reduces the Profibrotic Bronchial Fibroblasts Transition Associated with Asthma

Subepithelial fibrosis is a component of the remodeling observed in the bronchial wall of patients diagnosed with asthma. In this process, human bronchial fibroblasts (HBFs) drive the fibroblast-to-myofibroblast transition (FMT) in response to transforming growth factor-β(1) (TGF-β(1)), which activa...

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Detalles Bibliográficos
Autores principales: Paw, Milena, Wnuk, Dawid, Nit, Kinga, Bobis-Wozowicz, Sylwia, Szychowski, Rafał, Ślusarczyk, Alicja, Madeja, Zbigniew, Michalik, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657816/
https://www.ncbi.nlm.nih.gov/pubmed/34884593
http://dx.doi.org/10.3390/ijms222312790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657816/
https://www.ncbi.nlm.nih.gov/pubmed/34884593
http://dx.doi.org/10.3390/ijms222312790

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