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Splice-Variant Knock-Out of TGFβ Receptors Perturbates the Proteome of Ovarian Carcinoma Cells

The aim of this study was to analyze the biological role of different transforming growth factor-β (TGFβ) receptor splice variants in ovarian carcinoma (OC). Specific receptor variant knockouts (KO) were prepared using the CRISPR/Cas9 genome editing system in two OC cell lines, TβRI variant 1 (TβRIv...

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Detalles Bibliográficos
Autores principales: Jacobs Catane, Liora, Moshel, Ofra, Smith, Yoav, Davidson, Ben, Reich, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657817/
https://www.ncbi.nlm.nih.gov/pubmed/34884451
http://dx.doi.org/10.3390/ijms222312647