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MT1-MMP Cooperates with TGF-β Receptor-Mediated Signaling to Trigger SNAIL and Induce Epithelial-to-Mesenchymal-like Transition in U87 Glioblastoma Cells

Epithelial-to-mesenchymal transition (EMT) recapitulates metastasis and can be induced in vitro through transforming growth factor (TGF)-β signaling. A role for MMP activity in glioblastoma multiforme has been ascribed to EMT, but the molecular crosstalk between TGF-β signaling and membrane type 1 M...

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Detalles Bibliográficos
Autores principales: Djediai, Souad, Gonzalez Suarez, Narjara, El Cheikh-Hussein, Layal, Rodriguez Torres, Sahily, Gresseau, Loraine, Dhayne, Sheraz, Joly-Lopez, Zoé, Annabi, Borhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657819/
https://www.ncbi.nlm.nih.gov/pubmed/34884812
http://dx.doi.org/10.3390/ijms222313006