Cargando…

CCAAT/Enhancer-Binding Protein ε(27) Antagonism of GATA-1 Transcriptional Activity in the Eosinophil Is Mediated by a Unique N-Terminal Repression Domain, Is Independent of Sumoylation and Does Not Require DNA Binding

CCAAT/enhancer binding protein epsilon (C/EBPε) is required for eosinophil differentiation, lineage-specific gene transcription, and expression of C/EBPε(32) and shorter 27kD and 14kD isoforms is developmentally regulated during this process. We previously defined the 27kD isoform (C/EBPε(27)) as an...

Descripción completa

Detalles Bibliográficos
Autores principales: Stankiewicz, Monika J., Du, Jian, Martinico, Dominick, Ackerman, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657826/
https://www.ncbi.nlm.nih.gov/pubmed/34884493
http://dx.doi.org/10.3390/ijms222312689