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Doxorubicin Impairs Smooth Muscle Cell Contraction: Novel Insights in Vascular Toxicity

Clinical and animal studies have demonstrated that chemotherapeutic doxorubicin (DOX) increases arterial stiffness, a predictor of cardiovascular risk. Despite consensus about DOX-impaired endothelium-dependent vasodilation as a contributing mechanism, some studies have reported conflicting results...

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Detalles Bibliográficos
Autores principales: Bosman, Matthias, Krüger, Dustin N., Favere, Kasper, Wesley, Callan D., Neutel, Cédric H. G., Van Asbroeck, Birgit, Diebels, Owen R., Faes, Bart, Schenk, Timen J., Martinet, Wim, De Meyer, Guido R. Y., Van Craenenbroeck, Emeline M., Guns, Pieter-Jan D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657832/
https://www.ncbi.nlm.nih.gov/pubmed/34884612
http://dx.doi.org/10.3390/ijms222312812