Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae

The zebrafish (Danio rerio) embryo is gaining interest as a bridging tool between in-vitro and in-vivo developmental toxicity studies. However, cytochrome P450 (CYP)-mediated drug metabolism in this model is still under debate. Therefore, we investigated the potential of zebrafish embryos and larvae...

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Detalles Bibliográficos
Autores principales: Bars, Chloé, Hoyberghs, Jente, Valenzuela, Allan, Buyssens, Laura, Ayuso, Miriam, Van Ginneken, Chris, Labro, Alain J., Foubert, Kenn, Van Cruchten, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657848/
https://www.ncbi.nlm.nih.gov/pubmed/34884510
http://dx.doi.org/10.3390/ijms222312696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657848/
https://www.ncbi.nlm.nih.gov/pubmed/34884510
http://dx.doi.org/10.3390/ijms222312696

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