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EGFR Transgene Stimulates Spontaneous Formation of MCF7 Breast Cancer Cells Spheroids with Partly Loss of HER3 Receptor

Multicellular spheroids with 3D cell–cell interactions are a useful model to simulate the growth conditions of cancer. There is evidence that in tumor spheroids, the expression of various essential molecules is changed compared to the adherent form of cell cultures. These changes include growth fact...

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Detalles Bibliográficos
Autores principales: Troitskaya, Olga, Novak, Diana, Nushtaeva, Anna, Savinkova, Maria, Varlamov, Mikhail, Ermakov, Mikhail, Richter, Vladimir, Koval, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657849/
https://www.ncbi.nlm.nih.gov/pubmed/34884742
http://dx.doi.org/10.3390/ijms222312937