Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells

Under the influence of transforming growth factor-beta (TGFβ), glioma-associated microglia produce molecules that promote glioma growth and invasion. Olfactomedin-like 3 (Olfml3), a novel, secreted glycoprotein, is known to promote several non-CNS cancers. While it is a direct TGFβ1 target gene in m...

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Detalles Bibliográficos
Autores principales: Toedebusch, Ryan G., Lucchesi, Christopher A., Debebe, Eshetu T., Wittenburg, Luke A., Chen, Xinbin, Toedebusch, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657851/
https://www.ncbi.nlm.nih.gov/pubmed/34884869
http://dx.doi.org/10.3390/ijms222313052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657851/
https://www.ncbi.nlm.nih.gov/pubmed/34884869
http://dx.doi.org/10.3390/ijms222313052

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