Cytotoxic Aβ Protofilaments Are Generated in the Process of Aβ Fibril Disaggregation

Significant research on Alzheimer’s disease (AD) has demonstrated that amyloid β (Aβ) oligomers are toxic molecules against neural cells. Thus, determining the generation mechanism of toxic Aβ oligomers is crucial for understanding AD pathogenesis. Aβ fibrils were reported to be disaggregated by tre...

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Detalles Bibliográficos
Autores principales: Kaku, Toshisuke, Tsukakoshi, Kaori, Ikebukuro, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657853/
https://www.ncbi.nlm.nih.gov/pubmed/34884584
http://dx.doi.org/10.3390/ijms222312780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657853/
https://www.ncbi.nlm.nih.gov/pubmed/34884584
http://dx.doi.org/10.3390/ijms222312780

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