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Cytotoxic Aβ Protofilaments Are Generated in the Process of Aβ Fibril Disaggregation
Significant research on Alzheimer’s disease (AD) has demonstrated that amyloid β (Aβ) oligomers are toxic molecules against neural cells. Thus, determining the generation mechanism of toxic Aβ oligomers is crucial for understanding AD pathogenesis. Aβ fibrils were reported to be disaggregated by tre...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657853/ https://www.ncbi.nlm.nih.gov/pubmed/34884584 http://dx.doi.org/10.3390/ijms222312780 |