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Discovery of Novel Dihydrolipoamide S-Succinyltransferase Inhibitors Based on Fragment Virtual Screening

A series of new oxadiazole sulfone derivatives containing an amide moiety was synthesized based on fragment virtual screening to screen high-efficiency antibacterial agents for rice bacterial diseases. All target compounds showed greater bactericidal activity than commercial bactericides. 3-(4-fluor...

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Detalles Bibliográficos
Autores principales: Wei, Chengqian, Huang, Junjie, Wang, Yu, Chen, Yifang, Luo, Xin, Wang, Shaobo, Wu, Zengxue, Chen, Jixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657855/
https://www.ncbi.nlm.nih.gov/pubmed/34884760
http://dx.doi.org/10.3390/ijms222312953