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Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform

Dystrophin is a 427 kDa protein that stabilizes muscle cell membranes through interactions with the cytoskeleton and various membrane-associated proteins. Loss of dystrophin as in Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle weakness and cardiac dysfunction. Multiple promoter...

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Detalles Bibliográficos
Autores principales: Lim, Kenji Rowel Q., Shah, Md Nur Ahad, Woo, Stanley, Wilton-Clark, Harry, Zhabyeyev, Pavel, Wang, Faqi, Maruyama, Rika, Oudit, Gavin Y., Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657860/
https://www.ncbi.nlm.nih.gov/pubmed/34884423
http://dx.doi.org/10.3390/ijms222312617