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Characterization of the Transient Deficiency of PKC Isozyme Levels in Immature Cord Blood T Cells and Its Connection to Anti-Allergic Cytokine Profiles of the Matured Cells

Cord blood T cells (CBTC) from a proportion of newborns express low/deficient levels of some protein kinase C (PKC) isozymes, with low levels of PKCζ correlating with increased risk of developing allergy and associated decrease in interferon-gamma (IFN-γ) producing T cells. Interestingly, these lowe...

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Detalles Bibliográficos
Autores principales: Perveen, Khalida, Quach, Alex, Stark, Michael J., Prescott, Susan L., Barry, Simon C., Hii, Charles S., Ferrante, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657888/
https://www.ncbi.nlm.nih.gov/pubmed/34884454
http://dx.doi.org/10.3390/ijms222312650