Redefining the Role of ADAM17 in Renal Proximal Tubular Cells and Its Implications in an Obese Mouse Model of Pre-Diabetes

Acute and chronic kidney lesions induce an increase in A Disintegrin And Metalloproteinase domain 17 (ADAM17) that cleaves several transmembrane proteins related to inflammatory and fibrotic pathways. Our group has demonstrated that renal ADAM17 is upregulated in diabetic mice and its inhibition dec...

Descripción completa

Detalles Bibliográficos
Autores principales: Palau, Vanesa, Villanueva, Sofia, Jarrín, Josué, Benito, David, Márquez, Eva, Rodríguez, Eva, Soler, María José, Oliveras, Anna, Gimeno, Javier, Sans, Laia, Crespo, Marta, Pascual, Julio, Barrios, Clara, Riera, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657896/
https://www.ncbi.nlm.nih.gov/pubmed/34884897
http://dx.doi.org/10.3390/ijms222313093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657896/
https://www.ncbi.nlm.nih.gov/pubmed/34884897
http://dx.doi.org/10.3390/ijms222313093

Ejemplares similares