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Substrate-Dependent Trans-Stimulation of Organic Cation Transporter 2 Activity

The search of substrates for solute carriers (SLCs) constitutes a major issue, owing notably to the role played by some SLCs, such as the renal electrogenic organic cation transporter (OCT) 2 (SLC22A2), in pharmacokinetics, drug–drug interactions and drug toxicity. For this purpose, substrates have...

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Detalles Bibliográficos
Autores principales: Lefèvre, Charles R., Le Vée, Marc, Gaubert, Sophie, Jouan, Elodie, Bruyere, Arnaud, Moreau, Caroline, Fardel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657912/
https://www.ncbi.nlm.nih.gov/pubmed/34884730
http://dx.doi.org/10.3390/ijms222312926