C57BL/6 Background Attenuates mHTT Toxicity in the Striatum of YAC128 Mice

Mouse models are frequently used to study Huntington’s disease (HD). The onset and severity of neuronal and behavioral pathologies vary greatly between HD mouse models, which results from different huntingtin expression levels and different CAG repeat length. HD pathology appears to depend also on t...

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Detalles Bibliográficos
Autores principales: Back, Michaela K., Kurzawa, Johanna, Ruggieri, Sonia, von Engelhardt, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657915/
https://www.ncbi.nlm.nih.gov/pubmed/34884469
http://dx.doi.org/10.3390/ijms222312664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657915/
https://www.ncbi.nlm.nih.gov/pubmed/34884469
http://dx.doi.org/10.3390/ijms222312664

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