Cargando…
Combined Pharmacophore and Grid-Independent Molecular Descriptors (GRIND) Analysis to Probe 3D Features of Inositol 1,4,5-Trisphosphate Receptor (IP(3)R) Inhibitors in Cancer
Inositol 1, 4, 5-trisphosphate receptor (IP(3)R)-mediated Ca(2+) signaling plays a pivotal role in different cellular processes, including cell proliferation and cell death. Remodeling Ca(2+) signals by targeting the downstream effectors is considered an important hallmark in cancer progression. Des...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657927/ https://www.ncbi.nlm.nih.gov/pubmed/34884798 http://dx.doi.org/10.3390/ijms222312993 |