Structural Characterization of the Interaction of Hypoxia Inducible Factor-1 with Its Hypoxia Responsive Element at the −964G > A Variation Site of the HLA-G Promoter Region

Human Antigen Leukocyte-G (HLA-G) gene encodes an immune checkpoint molecule that has restricted tissue expression in physiological conditions; however, the gene may be induced in hypoxic conditions by the interaction with the hypoxia inducible factor-1 (HIF1). Hypoxia regulatory elements (HRE) loca...

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Detalles Bibliográficos
Autores principales: Alves, Cinthia C., Donadi, Eduardo A., Giuliatti, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657931/
https://www.ncbi.nlm.nih.gov/pubmed/34884849
http://dx.doi.org/10.3390/ijms222313046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657931/
https://www.ncbi.nlm.nih.gov/pubmed/34884849
http://dx.doi.org/10.3390/ijms222313046

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