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Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery

Maintenance of genomic integrity is crucial for cell survival. As such, elegant DNA damage response (DDR) systems have evolved to ensure proper repair of DNA double-strand breaks (DSBs) and other lesions that threaten genomic integrity. Towards this end, most therapeutic studies have focused on unde...

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Detalles Bibliográficos
Autores principales: Hayman, Thomas J., Glazer, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657976/
https://www.ncbi.nlm.nih.gov/pubmed/34884568
http://dx.doi.org/10.3390/ijms222312761