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Glitazone Treatment Rescues Phenotypic Deficits in a Fly Model of Gaucher/Parkinson’s Disease

Parkinson’s Disease (PD) is the most common movement disorder, and the strongest genetic risk factor for PD is mutations in the glucocerebrosidase gene (GBA). Mutations in GBA also lead to the development of Gaucher Disease (GD), the most common type of lysosomal storage disorder. Current therapeuti...

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Detalles Bibliográficos
Autores principales: Shola-Dare, Oluwanifemi, Bailess, Shelby, Flores, Carlos C., Vanderheyden, William M., Gerstner, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657993/
https://www.ncbi.nlm.nih.gov/pubmed/34884544
http://dx.doi.org/10.3390/ijms222312740