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Bifunctional Inhibitors of Influenza Virus Neuraminidase: Molecular Design of a Sulfonamide Linker

The growing resistance of the influenza virus to widely used competitive neuraminidase inhibitors occupying the active site of the enzyme requires the development of bifunctional compounds that can simultaneously interact with other regulatory sites on the protein surface. When developing such an in...

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Detalles Bibliográficos
Autores principales: Evteev, Sergei, Nilov, Dmitry, Polenova, Aleksandra, Švedas, Vytas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657994/
https://www.ncbi.nlm.nih.gov/pubmed/34884917
http://dx.doi.org/10.3390/ijms222313112