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Bifunctional Inhibitors of Influenza Virus Neuraminidase: Molecular Design of a Sulfonamide Linker
The growing resistance of the influenza virus to widely used competitive neuraminidase inhibitors occupying the active site of the enzyme requires the development of bifunctional compounds that can simultaneously interact with other regulatory sites on the protein surface. When developing such an in...
Autores principales: | Evteev, Sergei, Nilov, Dmitry, Polenova, Aleksandra, Švedas, Vytas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657994/ https://www.ncbi.nlm.nih.gov/pubmed/34884917 http://dx.doi.org/10.3390/ijms222313112 |
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