Opposing Effects of Chelidonine on Tyrosine and Serine Phosphorylation of STAT3 in Human Uveal Melanoma Cells

STAT3 is a transcription factor that regulates various cellular processes with oncogenic potential, thereby promoting tumorigenesis when activated uncontrolled. STAT3 activation is mediated by its tyrosine phosphorylation, triggering dimerization and nuclear translocation. STAT3 also contains a seri...

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Detalles Bibliográficos
Autores principales: Csomós, István, Nagy, Péter, Filep, Csenge, Rebenku, István, Nizsalóczki, Enikő, Kovács, Tamás, Vámosi, György, Mátyus, László, Bodnár, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658041/
https://www.ncbi.nlm.nih.gov/pubmed/34884773
http://dx.doi.org/10.3390/ijms222312974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658041/
https://www.ncbi.nlm.nih.gov/pubmed/34884773
http://dx.doi.org/10.3390/ijms222312974

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