Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores

The T-box transcription factor Eomesodermin (Eomes) promotes the expression of interferon-γ (IFN-γ). We recently reported that the small molecule inhibitors, TPCA-1 and IKK-16, which target nuclear factor κB (NF-κB) activation, moderately reduced Eomes-dependent IFN-γ expression in mouse lymphoma BW...

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Detalles Bibliográficos
Autores principales: Tanaka, Yumiko, Nakao, Ayaka, Miyake, Yasunobu, Higashi, Yukina, Tanigaki, Riho, Kataoka, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658103/
https://www.ncbi.nlm.nih.gov/pubmed/34884902
http://dx.doi.org/10.3390/ijms222313098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658103/
https://www.ncbi.nlm.nih.gov/pubmed/34884902
http://dx.doi.org/10.3390/ijms222313098

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