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Control of TRPM3 Ion Channels by Protein Kinase CK2-Mediated Phosphorylation in Pancreatic β-Cells of the Line INS-1

In pancreatic β-cells of the line INS-1, glucose uptake and metabolism induce the openings of Ca(2+)-permeable TRPM3 channels that contribute to the elevation of the intracellular Ca(2+) concentration and the fusion of insulin granules with the plasma membrane. Conversely, glucose-induced Ca(2+) sig...

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Detalles Bibliográficos
Autores principales: Becker, Alexander, Götz, Claudia, Montenarh, Mathias, Philipp, Stephan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658122/
https://www.ncbi.nlm.nih.gov/pubmed/34884938
http://dx.doi.org/10.3390/ijms222313133