Modulation of Prostanoids Profile and Counter-Regulation of SDF-1α/CXCR4 and VIP/VPAC2 Expression by Sitagliptin in Non-Diabetic Rat Model of Hepatic Ischemia-Reperfusion Injury

Molecular mechanisms underlying the beneficial effect of sitagliptin repurposed for hepatic ischemia-reperfusion injury (IRI) are poorly understood. We aimed to evaluate the impact of IRI and sitagliptin on the hepatic profile of eicosanoids (LC-MS/MS) and expression/concentration (RTqPCR/ELISA) of...

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Detalles Bibliográficos
Autores principales: Krzystek-Korpacka, Małgorzata, Fleszar, Mariusz G., Fortuna, Paulina, Gostomska-Pampuch, Kinga, Lewandowski, Łukasz, Piasecki, Tomasz, Kosyk, Bogna, Szeląg, Adam, Trocha, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658172/
https://www.ncbi.nlm.nih.gov/pubmed/34884960
http://dx.doi.org/10.3390/ijms222313155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658172/
https://www.ncbi.nlm.nih.gov/pubmed/34884960
http://dx.doi.org/10.3390/ijms222313155

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