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A Brief Journey through Protein Misfolding in Transthyretin Amyloidosis (ATTR Amyloidosis)

Transthyretin (TTR) amyloidogenesis involves the formation, aggregation, and deposition of amyloid fibrils from tetrameric TTR in different organs and tissues. While the result of amyloidoses is the accumulation of amyloid fibrils resulting in end-organ damage, the nature, and sequence of the molecu...

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Detalles Bibliográficos
Autores principales: Gonzalez-Duarte, Alejandra, Ulloa-Aguirre, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658192/
https://www.ncbi.nlm.nih.gov/pubmed/34884963
http://dx.doi.org/10.3390/ijms222313158