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A Brief Journey through Protein Misfolding in Transthyretin Amyloidosis (ATTR Amyloidosis)
Transthyretin (TTR) amyloidogenesis involves the formation, aggregation, and deposition of amyloid fibrils from tetrameric TTR in different organs and tissues. While the result of amyloidoses is the accumulation of amyloid fibrils resulting in end-organ damage, the nature, and sequence of the molecu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658192/ https://www.ncbi.nlm.nih.gov/pubmed/34884963 http://dx.doi.org/10.3390/ijms222313158 |