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T Cell Fitness and Autologous CAR T Cell Therapy in Haematologic Malignancy

A range of emerging therapeutic approaches for the treatment of cancer aim to induce or augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy (CTT) is one such approach that utilises the patient’s own T cells, engineered ex vivo to target cell surface antigens, to elimi...

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Detalles Bibliográficos
Autores principales: Mehta, Palak H., Fiorenza, Salvatore, Koldej, Rachel M., Jaworowski, Anthony, Ritchie, David S., Quinn, Kylie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658247/
https://www.ncbi.nlm.nih.gov/pubmed/34899742
http://dx.doi.org/10.3389/fimmu.2021.780442