Imidazole Analogs of Vascular-Disrupting Combretastatin A-4 with Pleiotropic Efficacy against Resistant Colorectal Cancer Models

Specific targeting of the tumoral vasculature by vascular-disrupting agents (VDA), of which combretastatin A-4 (CA-4) is a main representative, has been considered a new therapeutic strategy against multidrug-resistant tumors. In addition, CA-4 and analogs are tubulin-targeting agents and can exert...

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Detalles Bibliográficos
Autores principales: Reipsch, Franziska, Biersack, Bernhard, Lucas, Henrike, Schobert, Rainer, Mueller, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658273/
https://www.ncbi.nlm.nih.gov/pubmed/34884888
http://dx.doi.org/10.3390/ijms222313082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658273/
https://www.ncbi.nlm.nih.gov/pubmed/34884888
http://dx.doi.org/10.3390/ijms222313082

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