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A Novel Single-Step-Labeled (212)Pb-CaCO(3) Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice
Lead-212 is recognized as a promising radionuclide for targeted alpha therapy for tumors. Many studies of (212)Pb-labeling of various biomolecules through bifunctional chelators have been conducted. Another approach to exploiting the cytotoxic effect is coupling the radionuclide to a microparticle a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658347/ https://www.ncbi.nlm.nih.gov/pubmed/34885283 http://dx.doi.org/10.3390/ma14237130 |