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A Novel Single-Step-Labeled (212)Pb-CaCO(3) Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice

Lead-212 is recognized as a promising radionuclide for targeted alpha therapy for tumors. Many studies of (212)Pb-labeling of various biomolecules through bifunctional chelators have been conducted. Another approach to exploiting the cytotoxic effect is coupling the radionuclide to a microparticle a...

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Detalles Bibliográficos
Autores principales: Li, Ruth Gong, Lindland, Kim, Bønsdorff, Tina Bjørnlund, Westrøm, Sara, Larsen, Roy Hartvig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658347/
https://www.ncbi.nlm.nih.gov/pubmed/34885283
http://dx.doi.org/10.3390/ma14237130