Exploration of the Effect on Genome-Wide DNA Methylation by miR-143 Knock-Out in Mice Liver

MiR-143 play an important role in hepatocellular carcinoma and liver fibrosis via inhibiting hepatoma cell proliferation. DNA methyltransferase 3 alpha (DNMT3a), as a target of miR-143, regulates the development of primary organic solid tumors through DNA methylation mechanisms. However, the effect...

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Detalles Bibliográficos
Autores principales: Chen, Xingping, Luo, Junyi, Liu, Jie, Chen, Ting, Sun, Jiajie, Zhang, Yongliang, Xi, Qianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658369/
https://www.ncbi.nlm.nih.gov/pubmed/34884879
http://dx.doi.org/10.3390/ijms222313075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658369/
https://www.ncbi.nlm.nih.gov/pubmed/34884879
http://dx.doi.org/10.3390/ijms222313075

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