Genetic Background Influences Severity of Colonic Aganglionosis and Response to GDNF Enemas in the Holstein Mouse Model of Hirschsprung Disease

Hirschsprung disease is a congenital malformation where ganglia of the neural crest-derived enteric nervous system are missing over varying lengths of the distal gastrointestinal tract. This complex genetic condition involves both rare and common variants in dozens of genes, many of which have been...

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Detalles Bibliográficos
Autores principales: Soret, Rodolphe, Lassoued, Nejia, Bonnamour, Grégoire, Bernas, Guillaume, Barbe, Aurélie, Pelletier, Mélanie, Aichi, Manon, Pilon, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658428/
https://www.ncbi.nlm.nih.gov/pubmed/34884944
http://dx.doi.org/10.3390/ijms222313140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658428/
https://www.ncbi.nlm.nih.gov/pubmed/34884944
http://dx.doi.org/10.3390/ijms222313140

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