Depletion of Lipocalin 2 (LCN2) in Mice Leads to Dysbiosis and Persistent Colonization with Segmented Filamentous Bacteria

Lipocalin 2 (LCN2) mediates key roles in innate immune responses. It has affinity for many lipophilic ligands and binds various siderophores, thereby limiting bacterial growth by iron sequestration. Furthermore, LCN2 protects against obesity and metabolic syndrome by interfering with the composition...

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Detalles Bibliográficos
Autores principales: Klüber, Patrick, Meurer, Steffen K., Lambertz, Jessica, Schwarz, Roman, Zechel-Gran, Silke, Braunschweig, Till, Hurka, Sabine, Domann, Eugen, Weiskirchen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658549/
https://www.ncbi.nlm.nih.gov/pubmed/34884961
http://dx.doi.org/10.3390/ijms222313156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658549/
https://www.ncbi.nlm.nih.gov/pubmed/34884961
http://dx.doi.org/10.3390/ijms222313156

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