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Depletion of Lipocalin 2 (LCN2) in Mice Leads to Dysbiosis and Persistent Colonization with Segmented Filamentous Bacteria
Lipocalin 2 (LCN2) mediates key roles in innate immune responses. It has affinity for many lipophilic ligands and binds various siderophores, thereby limiting bacterial growth by iron sequestration. Furthermore, LCN2 protects against obesity and metabolic syndrome by interfering with the composition...
Autores principales: | Klüber, Patrick, Meurer, Steffen K., Lambertz, Jessica, Schwarz, Roman, Zechel-Gran, Silke, Braunschweig, Till, Hurka, Sabine, Domann, Eugen, Weiskirchen, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658549/ https://www.ncbi.nlm.nih.gov/pubmed/34884961 http://dx.doi.org/10.3390/ijms222313156 |
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