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Amination of 5-Spiro-Substituted 3-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones

The 3-hydroxy-1,5-dihydro-2H-pyrrol-2-one motif is a valuable scaffold in drug discovery. The replacement of the 3-oxy fragment in 3-hydroxy-1,5-dihydro-2H-pyrrol-2-ones-based compounds with a 3-amino one (3-amino analogs of 3-hydroxy-1,5-dihydro-2H-pyrrol-2-ones, 3-amino-1,5-dihydro-2H-pyrrol-2-one...

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Detalles Bibliográficos
Autores principales: Khramtsova, Ekaterina E., Lystsova, Ekaterina A., Khokhlova, Evgeniya V., Dmitriev, Maksim V., Maslivets, Andrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658906/
https://www.ncbi.nlm.nih.gov/pubmed/34885757
http://dx.doi.org/10.3390/molecules26237179